The chaps at Zero2Ten who are fast becoming one of my favourite blogs and CRM companies out, they have created a lot of really good videos on CRM 2011.
Today there have created a free Solution which will allow you to make skype calls directly from CRM contact record.
The tool has also been certified as compatible with Microsoft Dynamics CRM 2011 and can be found on the Microsoft Dynamics Marketplace.
You can download the solution here, you have to fill in some details but this is a fair trade as you get the skype solution completely free.
Here you can see a screen shot of skype enabled within CRM 2011